BOOK PUBLICATION:
Dr Nirmal M Shah, Synthesis and Reactions of Some Bio-active Pyrazolopyrimidines, LAMBERT Academic (International publication), 2018, 978-3-659-96461-9, https://images.our-assets.com/fullcover/2000x/9783659964619.jpg
Completed two Minor research projects sponsored by UGC and Gujcost.
PAPER PRESENTED
1) Presented Oral Paper in International conference held in MD, USA, 13th Green Chemistry and Engineering Conference on ‘Green pathways for the synthesis and ring cleavage of tetrazolopyrrolopyrimidines using eco friendly phase transfer catalysis’ during 23-25th June 2009.
2) Presented Oral Paper in International conference held in Ahmedabad, India, India-Canada Conference on Nucleophilic Displacements in fused pyrrolopyrimidines using eco friendly phase transfer catalysis during 6-8th January, 2010.
3) Presented Poster Paper in International conference held in Ahmedabad, India, India Conference on PTC Assisted Ring Cleavage of Some Notrogen heterocycles to Pyrimidines of Synthetic Importance during 6-8th February, 2012.
4) Presented a poster paper in International conference held in Ahmedabad on Synthesis of Novel bioactive N-substitutedpyridylpyrazole-4-carboxamides using T3P on ‘Current trends in Biological sciences in Medical Sciences’ organized by M. G. Science College, Ahmedabad 27-28 December 2015.
5) Presented a poster paper on ‘Synthesis of bioactive fused pyrimidines by SN reactions using Phase Transfer Catalysis’ in two days UGC sponsored Intrenational seminar on ‘Current trends in biological sciences in Medical Sciences’ organized by M. G. Science College, Ahmedabad 27-28 December 2015.
6) Presented Poster paper on ‘Utility and versatility of 2-bromopropeledenenitriles in the synthesis of nitrogen heterocycles’ in the National conference, UGC sponsored 32nd convention of chemist, organized by Indian Chemical Society, held at Jaipur, India in December 1995.
7) Presented Award paper on Synthesis of isomeric triazolopyrrolopyrimidines in the conference, UGC sponsored 33rd convention of chemist, organized by Indian Chemical Society, held at Coimbatore, India in December 1996.
8) Presented Poster paper on ‘PTC Assisted Nucleophilic Displacements in pyrrolo Pyrimidines’ in the National conference organized by North Gujarat University, held at Patan, India in January 2011.
9) Presented Award paper in one days UGC sponsored state level seminar, organized at Kadi Science College in February 2008 and won the prize.
10) Presented two papers in two days UGC sponsored state level seminar, on ‘Frontier advances in chemical sciences’ organized by M. G. Science College, Ahmedabad in March 2008.
11) Presented a paper on ‘Thorpe Reaction in the Synthesis of 2-Aminothiophenes Using eco friendly Phase-Transfer Catalysis’ in two days UGC sponsored state level seminar on ‘Environment and disaster risk management’ organized by M. G. Science College, Ahmedabad in January 2009,
12) Presented poster paper on ‘PTC assisted SN reactions in fused pyrimidines’ in two days UGC sponsored National level seminar on ‘Chemistry for sustainable development’ organized by M. G. Science College, Ahmedabad in December 2014.
13) Presented a poster paper on ‘T3P-propane phosponic acid anhydride, a green reagent in acid-amine coupling’ in two days UGC sponsored National level seminar on ‘Chemistry for sustainable development’ organized by M. G. Science College, Ahmedabad in December 2014.
14) Presented a poster paper on Acid-amine coupling in the synthesis of Novel N-substitutedpyridyl heteroarylcarboxamides using T3P in one day UGC sponsored National level seminar on ‘Chemistry for sustainable development’ organized by J&J Nadiad Science College, in December 2016.
15) Presented a poster paper on ‘Role of IQAC in higher education’ in one day seminar sponsored by UGC NACC, Bengaluru organized by M. G. Science College, Ahmedabad in October 2016.
16) Presented a poster paper on ‘PTC, the improved protocol in synthesis of pyridine hetrocycles’ in one days UGC sponsored National level seminar on ‘Innovative Approaches to Green Chemistry: Recent prospectives organized by Sheth M N Science College, Patan, 28th Jan2017 and won 1st prize.
17) Presented three poster papers in GUJCOST sponsored one day National Seminar at M G Science Institute, 26th Feb 2018 on (1 Microwave Irradiated Synthesis of Pyrazole-Carboxamides (2 Computational Study Of Pyrazolopyrimidines As Thymidylate Synthase Inhibitors & (3 Nanomaterial Based Medicine And Medical Aids
18) Presented a poster paper on Microwave supported synthesis of N-pyrazolyl pyrrolopyrimines, Shah Rina and Shah Nirmal in National conference organized by Sir PT Science college, Modasa, 28th April 2023.
Associated with research since last 17 years in the field of Synthetic Organic Chemistry in Organic Syntheses Laboratory, M. G. Science institute and successfully completed many projects based on synthetic industrial products. Studies on synthesis and reactions of amino substituted pyrroles, thiophenes, pyridines, pyrimidines, thiazoles, triazoles, tetrazoles, pyrazole have been undertaken for the construction of pyrrolopyrimidines, pyrrolopyrimidopyrimidines, tetrazolopyrrolopyrimidines, thienopyrimidopyrimidines, thienopyrrolopyrimidines, pyrroloquinazolines, isomeric triazolopyrrolopyrimidines, tetrazolopyrrolopyrimidines etc. using conventional as well as improved and efficient advanced ecofriendly techniques such as phase transfer catalysis, microwave irradiation and etc. Also working on catalysis for C-C and C-N cross coupling, micro and nanoemulsion techniques.
Publications
1) 2-Haloalkylidenepropanedinitriles in the synthesis of fused pyrimidines: Chaiatnya G. Dave and Rina D. Shah; Heterocycles; 48, 559(1998).
2) Synthesis of 7H-Tetrazolopyrrolopyrimidines and their reductive ring cleavage to 4-aminopyrrolopyrimidines: Chaitanya G. Dave and Rina D. Shah; J. Heterocycl. Chem.; 31, 1800(1999).
3) Gould-Jacob type of reaction in the synthesis of thieno[3,2-e]pyrrolo[1,2-c]pyrimidines: A comparison of classical heating and microwave irradiation: Chaitanya G. Dave and Rina D. Shah; Heterocycles; 51, 1819(1999).
4) Synthesis of Isomeric triazolopyrrolopyrimidines: Chaitanya G. Dave and Rina D. Shah; J. Heterocycl. Chem.; 37, 957(2000).
5) Chaitanya G. Dave and Rina D. Shah, Annellation of Triazole and Tetrazole ring system onto pyrrolo[2,3-d] pyrimidines: Synthesis of Tetrazolo[1,5-c]pyrrolo[3,2-e] pyrimidines Triazolo[1,5-c]pyrrolo[3,2-e]pyrimidines as antibacterial agents, Molecules, 7, 554 (2002).
6) Rina D. Shah and Nirmal Desai; An improved Synthesis and efficient chemoselective reduction of fused tetrazolopyrimidines under phase transfer conditions, Synthesis 19, 3275(2006).
7) Rina D. Shah and Nirmal Desai, Thorpe Cyclization in the synthesis of pyrazole using phase transfer condition, Synthetic Commun., 38, 316-327(2008), ISSN 0039-7911 print/1532-2432 online DOI: 10.1080/00397910701767023
8) Mukesh M. Jotani, Rina D. Shah, Jerry P. Jasinski and Ray J. Butcher; 7-(4-Bromophenyl)-9-phenyl-7H-pyrrolo[3,2- e]tetrazolo[1,5-c]pyrimidine, Acta Cryst. E66, o574(2010), ISSN 1600-5368
9) Rina D. Shah, Mukesh M. Jotani and Jerry P. Jasinski; 7-(4-Chlorophenyl)-9-phenyl-7H-pyrrolo[3,2-e]tetrazolo[1,5-c]pyrimidine; Acta Cryst. E66, o601–o602(2010), ISSN 1600-5368
10) Mukesh M. Jotani, Rina D. Shah and Jerry P. Jasinski; 7-(4-Methoxyphenyl)-5-methyl-9-phenyl-7Hpyrrolo[2,3 :4,5]pyrimido[1,6- d]tetrazole; Acta Cryst.E66, o212–o213 (2010). ISSN 1600-5368
11) Rina D. Shah, PTC Assisted Nucleophilic displacements in pyrrolopyrimidines, Chemistry for sustainable development, 19 (2011) 321.327, ISSN 1817-1818.
12) Rina D. Shah, A comparative Studies on 3-aminothiophenes using PTC, EJChem, vol 8(1), 368-372., ISSN: 0973-4945 (2010)
13) Rina D. Shah, Mukesh M. Jotani and Edward R. T. Tiekink; 12-(4-Chlorophenyl)-7-methyl-10-phenyl-3,4,5,6,8,10-hexaazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaene; Acta Cryst. (2010). E66, o3305, ISSN 1600-5368
14) Mukesh M. Jotani, Rina D. Shah and Edward R. T. Tiekink ;12-(4-Methoxyphenyl)-10-phenyl-3,4,5,6,8,10-hexaazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaene; Acta Cryst. (2010). E66, o805, ISSN 1600-5368
15) Shah Rina, Shah Nirmal, Ramani Vivek, Novel Synthesis of Tetrazolopyrrolopyrimidines as Antifungal agents Int J Sci Res,5, 626, 2016, ISIN 2319-7064
16) Shah Rina, Shah Nirmal, Ramani Vivek, Shah Dhaval, A Rapid Green Three component synthesis of 4,6-diarylpyridine-2(1H)-ones, Int J Sci Res Chem, 1, 44-47, 2016. ISSN 2456-8457.
17) Shah Rina, Shah Nirmal M and Ramani Vivek C, Microwave Assisted Gould-Jacob Reaction in the Synthesis of Furopyrimidopyrimidines and Their Transformation via Ring Opening to Aminoesters, Asian J Chem, Vol 29(11), 2750-54, 2017. ISSN 0975-427X
18) Shah Rina D and Shah Nirmal M, A simple and expedient liquid-liquid PTC assisted synthesis of bio-active pyrazolotetrazolopyrimidines, Int Res J Nat and Applied Sci., vol, 4(8), 21-31, 2017 ISSN 2349-4077, IF5.46
19) Shah Rina, and Shah Nirmal M, Phase Transfer Catalysis Aided Synthesis of Pyrazolopyrimidinemines by Chemoselective Reductive Ring Opening, IOSR-JAC, vol 10(8), 51-54. 2017 ISSN 2278-5736 IF <1IF 3.145
20) Shah Rina, Shah Nirmal M, Ramani Vivek C, Microwave Supported Solvent Free Reaction Of EMME In The Synthesis Of Pyrazolopyrimidopyrimidines, Asian J Applied Chemistry Research, Vol1, 1-9, 2018
21) Rina D. Shah, Ramani Vivek C., Mukesh M. Jotani and Edward R. T. Tiekink; N-(6-methoxypyridin-2-yl)-1-pyridin-2-ylmethyl)-1H-pyrazole carboxamide: crystal structure aand Hirshfeld surface analysis, Acta Cryst. E74, o3305, 2018. ISSN 2056-9890
22) Rina D Shah, Ramani Vivek C and Nirmal M shah ‘A Rapid Phase Transfer Catalyzed Heteroarylation by C-O Coupling and Ring Opening of Isopropylidene Glycerol in Synthesis of (Pyrazolopyrimidin-4-yloxy)propane-1,2-diols’ Asian J Chemistry, Vol 30(10), 2352-2356, 2018, ISSN 0975-427X
23) Rina D Shah, Ramani Vivek C and Nirmal M Shah ‘Montmorillonite K-10 supported rapid synthesis of 4-Pyrazolylpyrrolopyrimidines’ Asian J Organic & Medicinal Chemistry, Vol 3, 102-106, 2018, ISSN 2456-8937
24) Rina D Shah, Ramani Vivek C and Nirmal M Shah ‘Review on Pyrazolopyrimidopyrimidines Scaffold’ Heterocyclic Letters, 14, Vol 4, 2024, ISSN : (print) 2231–3087 / (online) 2230-9632
