Course Outcome

• Understand the generation, structure, stability, and reactions of carbocations, carbanions, free radicals, carbenes, nitrenes, and aryne, enabling the identification and analysis of these reactive intermediates in organic reactions.
• Gain proficiency in applying Huckel’s rule and understanding the concept of aromaticity, distinguishing between aromatic, anti-aromatic, and non-aromatic systems, and utilizing Frost circle diagrams for cyclobutadiene and benzene to analyze their aromaticity.
• Acquire knowledge of nucleophilic substitution reactions (SN1 and SN2) including their mechanisms, stereochemistry, leaving group effects, and the influence of reaction mediums, facilitating the understanding and prediction of substitution reactions in organic synthesis.
• Master the mechanisms and stereochemistry of electrophilic substitution reactions (SE1 and SE2), enabling the interpretation and prediction of substitution reactions involving electrophilic reagents.
• Develop proficiency in understanding and predicting addition reactions of alkenes and alkynes, as well as elimination reactions (E1 and E2), including Zaitsev’s rule, dehydration of alcohols, dehydrohalogenation of haloalkanes, and Hoffman elimination, for application in organic synthesis.
• Gain a comprehensive understanding of various rearrangement reactions, including carbon-carbon, carbon-nitrogen, and carbon-oxygen rearrangements, their mechanisms, reactions, and applications in organic synthesis, enabling the design and execution of complex synthetic pathways.